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The force can denature (damage) the peptide molecules, reducing potency

Comparative Effectiveness of Once-Weekly Glucagon-Like Peptide-1 Receptor Agonists With Regard to 6-Month Glycaemic Control and Weight Outcomes in Patients With Type 2 Diabetes

Directions for Future Research: Investigations should focus on confirming the efficacy of tirzepatide in type 1 diabetes, elucidating the neuroprotective potential of GLP-1/GIP dual agonists, optimizing perioperative protocols, and facilitating the clinical translation of novel multi-receptor agonists