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Therefore, we decided to focus on the most recent data on approved gliptins in this review

tirzepatide is contraindicated in individuals with personal or family history of medullary thyroid carcinoma or in patients with multiple endocrine neoplasia type 2 syndromes (54, 61)
Cardiovascular Benefits: Positive impact on cardiovascular health, reducing the risk of heart-related conditions

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Through HDAC6 inhibition, the pathway promotes the removal of damaged cellular components, reducing oxidative stress and enhancing cellular repair mechanisms in retinal cells ( 2.2.3 Beyond the eye In renal tubular cells ( + -dependent deacetylase SIRT1, reducing mitochondrial dysfunction and oxidative stress by decreasing ROS production, thereby preventing apoptosis induced by lipotoxicity