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We started with the lowest dose of 0.25 mg, and it took some time

A clinical trial of once-weekly TZT in T2DM patients illustrated that at 26 weeks of treatment, TZT led to the significant reduction of intercellular adhesion molecule 1 (ICAM-1), growth differentiation factor 15 (GDF-15), chitosan-3 like protein 1 (YKL-40), leptin and CRP compared to the baseline values

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( a, e, j ) Gold-standard Fourier Shell Correlation (FSC) curves for the consensus map (a), conformer 1 (e), and conformer 2 (j) showing overall nominal resolutions of 2.3 , 2.4 , and 2.5 , respectively

This was a specific and unexpected side effect, reported by a large percentage of patients, and, again, less likely to be a placebo effect