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The concerns include: Counterfeit or fraudulent labeling (e.g., fake pharmacies on the label or real pharmacies listed that didnt actually make the product) Potential quality problems (including improper storage/shipping) Dosing errors and adverse events, including cases requiring hospitalization Patients being prescribed doses that exceed FDA-approved labeling , with severe gastrointestinal side effects reported The agency also warns consumers about illegal sellers that market these drugs as for research purposes or not for human consumptionand emphasizes using legitimate, state-licensed pharmacies and prescriptions from licensed clinicians (FDA guidance for patients and providers)

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Once-weekly semaglutide for weight management: A clinical review

Kawai T, Sun B, Yoshino H, Feng D, Suzuki Y, Fukazawa M, et al

A large proportion of cross-sectional studies are heterogeneous in their design making it difficult to draw clear conclusions [35, 36]