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Knockdown of IL-10 receptor- or pharmacological inhibition of STAT3 activation abolished exenatide-induced -endorphin expression and its antiallodynic effects [63]
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Individual results varied significantly, with some participants losing over 20 percent and others losing less than 10 percent
Increased nausea, vomiting, early fullness even with small meals, bloating, and abdominal discomfort signal possible intolerance
SURMOUNT-MMO, NCT05556512) (Table 3)
