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Do not use Zepbound if you have had a serious allergic reaction to tirzepatide or any of the ingredients in Zepbound
Orforglipron (Foundayo): Early data suggests plateaus at 6 to 10 months, with 14 to 17 percent weight loss in maintenance trials
References Khan MAB, Hashim MJ, King JK, Govender RD, Mustafa H, Al Kaabi J
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28,36 Theoretically, the substitution of Gly 22 with Ala would make the -helix more stable, but increments in the affinity and activity were not found
