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The timing of supply-related discontinuations further illustrates how external factors, like national shortages or surges in demand, can abruptly disrupt continuity of care ( 13 15 )

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For example, researchers behind one small randomized controlled trial found that participants with obesity who ate half a fresh grapefruit before each meal for 12 weeks lost an average of 1.6 kilograms (kg), or about 3.5 pounds (lb), compared with a control group who lost 0.3 kg, which is less than 1 lb

C-reactive protein (CRP), a marker of systemic inflammation, typically decreases as weight drops

combines GIP-mediated insulin sensitization and adipose tissue effects with GLP-1 appetite suppression and glucose-dependent insulin s