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Bariatric surgery and GLP-1 medications are two evidence-based options your care team may discuss with you if you have a higher body mass index or BMI, or if you have weight-related health conditions such as type 2 diabetes

Decotiis says of the GLP-1 boom

When weight is lost quickly, the liver secretes extra cholesterol into bile, and reduced gallbladder motilitypartly due to the drug's effect on gastric emptyingcan lead to bile stasis

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Since arriving on the market in 2005 for the treatment of Type 2 diabetes, Circana said, the class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1s) have upended diabetes treatment and revolutionized how doctors and consumers approach weight management. These medications are designed to mimic the effects of a naturally occurring hormone that helps regulate blood sugar and slows digestion, which promotes the feeling of satiety, Circana added, noting that the first GLP-1 medication was approved for weight loss in 2014