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Weight Regain After Stopping Semaglutide: What the Evidence Shows The STEP 1 trial revealed that approximately 70% of weight lost during two years of semaglutide treatment returned within one year of discontinuation in patients who stopped the medication

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Foundayo (orforglipron): around 12% average weight loss at the highest dose in the ATTAIN-1 Phase 3 trial in adults with obesity, without type 2 diabetes

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