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Weight regain: When a person stops taking GLP-1 medications, the side effects of appetite suppression tend to go away, making weight gain common

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These studies aim to extend the therapeutic indications of currently approved GLP-1 molecules beyond their established roles in diabetes, obesity and CVD management

In the CNS, GLP-1Rs are expressed by neurons in the hippocampus, which is known to be a cognition-related brain region, and have been observed in neocortical pyramidal neurons (Hamilton and Holscher, 2009)