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Clinical trials show average weight loss of 1015% of baseline body weight over 1624 weeks when combined with lifestyle changes

Sodium alone won't solve the problem

(We can broaden it to "if nature makes it, take it, but if machines make it, you quit")

(2005b) Glucagon like peptide-1 is protective against myocardial ischemia/reperfusion injury when given either as a preconditioning mimetic or at reperfusion in an isolated rat heart model

This approach isn't suitable for everyone, particularly those with diabetes on insulin or sulfonylureas, pregnant or breastfeeding women, people with a history of eating disorders, those with kidney disease, or frail individuals