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Brand-Name GLP-1 Medications: Ozempic and Wegovy (semaglutide) Mounjaro and Zepbound (tirzepatide) FDA-approved with extensive clinical trial data Manufactured by pharmaceutical companies (Novo Nordisk, Eli Lilly) Cost $900-$1,350 per month without insurance May be covered by insurance (with restrictions) Come in pre-filled injection pens Compounded GLP-1 Medications: Same active ingredients as brand-name versions Made by FDA-registered compounding pharmacies Cost $199-$599 per month Not typically covered by insurance Available due to ongoing medication shortages May come in vials requiring manual injection or pre-filled syringes Are Compounded GLP-1s Safe

A Phase 1 multiple-ascending dose study of tirzepatide in Japanese participants with type 2 diabetes

Ships to your door Compounded in a 503-A pharmacy and delivered free in 35 business days

It will often be prescribed with the intention of being a long-term medication if the patient responds well and is able to continue increasing the dosage until it is maximized

Ethics declarations Competing interests All authors are employees of Heptares Therapeutics Ltd and are shareholders in Sosei Group Corporation