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A synthesis method and technology of semaglutide, applied in the field of polypeptide drug production, can solve the problems of high separation and purification, limited coupling site, purification of polypeptide fragments, etc., and achieve the solution of purification difficulty, alleviation of difficulty and rapid transformation

Conclusion In our experience, injectable semaglutide is preferred in patients with excess weight and shorter disease duration, while the oral formulation was used later and especially after therapeutic failure of previous therapies

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