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Diabetes 63 , 41864196 (2014)

Biomolecules 11:1000

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Peer-reviewed research published in journals including the New England Journal of Medicine has demonstrated statistically significant weight loss outcomes with semaglutide and tirzepatide in large randomized controlled trials involving thousands of participants tracked over periods of 68 weeks or longer

Conclusions GLP-1 receptor agonists significantly reduce major cardiovascular events and mortality in high-risk populations, with a favourable long-term safety profile