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Purpose of Review This review will summarize the most contemporary trials for glucagon-like peptide 1 receptor agonists (GLP1-RA) and sodium-glucose cotransporter 2 inhibitors (SGLT2-i) and present guidance on management and recommendations on adjunctive tapering of insulin in patients with insulin-dependent diabetes mellitus, which we term de-insulinization. Recent Findings GLP1-RA and SGLT2-i are the principal classes of diabetes medications evidencing cardiovascular benefit

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10:1 (Cinnamomum zeylanicum) (bark), Cayenne pepper (Capsicum annuum) (fruit) powder, Green tea extract (Camellia sinensis) (leaves), Alpha lipoic acid, Benfotiamine, Guarana seed powder (Paullinia cupana) (seed), Blood orange powder (citrus Sinensis) (fruit)
