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A multivitamin may be considered for patients with significantly reduced food intake or documented nutritional gaps, though the US Preventive Services Task Force notes insufficient evidence for routine multivitamin use for disease prevention in generally healthy adults

Another mouse study reported reduced fat mass and weight gain in an ovariectomy model [5]

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Patients on tirzepatide lost an average of 1.1 percent more lean body mass after three months and 2 percent more after 12 months of continuous use than those on semaglutide, based on an analysis by Massachusetts-based data analytics firm nference

Orlistat, a lipase inhibitor that reduces fat absorption, represents an alternative pharmacological option with a different mechanism of action, though it also carries gastrointestinal side effects including oily or fatty stools