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The Phase 2 data provides clear benchmarks: By week 4, most participants noticed reduced appetite and initial scale movement averaging 2-3% body weight reduction

Los resultados iniciales del estudio muestran que las personas pierden un mayor porcentaje de peso, hasta un 30% de su peso corporal, cuando toman retatrutida en comparacin con el placebo

[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Bednarz K., Kowalczyk K., Cwynar M., Czapla D., Czarkowski W., Kmita D., Nowak A., Madej P

The treatment with Liraglutide, exendin-4, or dulaglutide ameliorates the disease score in EAE and Cup-mice [115,116,117,121,123,124] independently of the dose, time, and via administration (subcutaneously or intraperitoneally)

While this might seem like a positive outcome, it actually reflects the body's attempt to conserve water in response to reduced intake.The researchers concluded that " GLP-1 receptor agonists reduce fluid intake and thirst perception in patients with primary polydipsia and could therefore be a treatment option for these patients"