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The neuroprotective effect of Liraglutide is mediated by glucagon-like peptide 1 receptor-mediated activation of cAMP/PKA/CREB pathway

Interestingly, LY294002 abolished the anti-apoptotic effects of GLP-1R, indicating that PI3K/Akt signaling may involve in the protective effects of GLP-1R

Additionally, if youre taking insulin or medications that stimulate insulin secretion, your overall regimen may need adjustment to reduce the risk of low blood sugar

Some require 12.5 or 15 mg to achieve adequate appetite suppression and weight loss

Acknowledgements Special thanks for all study team for their dedication and support in this study