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In hepatocytes, GLP-1 inhibits intracellular lipid production through the cAMP/AMPK signaling pathway, and this pathway can act directly upon LXR (Henquin, 2000)
Lastly, the systemic effects of GLP-1RAs, such as body weight loss [103] and potential reduction in muscle mass [104], pose significant challenges for elderly individuals with neurodegenerative diseases
Liu Y, Ruan B, Jiang H, Le S, Liu Y, Ao X, et al
