switching between glp-1 agonists ada Summary of the effects on HbA1c during transition after Frontiers | Mechanisms of action
Description
GLP-1 receptor agonists are mainly administered through the parenteral route due to poor oral bioavailability and degradation in the GI tract
doi: 10.1016/j.dsx.2021.102382 89 KristensenSLRrthRJhundPSDochertyKFSattarNPreissDet al
The actual future market size will likely be highly impacted by whether GLP-1RAs end up being used as longer-term treatments for individuals and how costs and pricing evolve over time
Despite that, the drug was well tolerated, even in patients with end-stage renal disease (ESRD), including those on dialysis
Reduce the risk of heart failure exacerbations by 40% and hospitalizations by 33%
