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Description
Alternative GLP-1 Therapies When Semaglutide Plateaus Tirzepatide is a dual GLP-1 and GIP receptor agonist that activates two appetite pathways simultaneously rather than one

There have been reports of gallbladder disease, including cholelithiasis and cholecystitis, possibly related to rapid weight loss

2024 Mar 21;10:e53086

Constipation is among the more commonly reported GI side effects of semaglutide and tirzepatide

The GLP-1 appetite suppression effect makes this worse
