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Monitoring heart health is also important, as both medications can impact cardiovascular health in different ways

[17] Whilst semaglutide primarily targets appetite centres in the hypothalamus, the broader distribution of GLP-1 receptors means that central nervous system effects cannot be entirely excluded, though this remains speculative without specific clinical evidence

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The patient reported improved physical health, including increased energy and reduced joint pain, and expressed satisfaction with his progress, which enhanced his self-esteem and motivation
