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Description
Efficacy of GLP-1 Agonists in Psychiatric Illnesses: A Scoping Review

GLP-1 itself is a hormone secreted by the intestines in response to food intake, which interacts with receptors in the brain to signal satiety and reduce appetite

The researcher assumes the protocol is not working because the early signal is not dramatic enough, when the more accurate read may be that the exposure curve has not matured yet

An optimized GLP-1/CCK fusion had enhanced efficacy to lower body weight in obese rodents relative to mono-agonist controls and their co-administration [946,947]

Pre-existing diabetes or insulin resistance represents the most significant risk factor
