glp 1 drugs history Reflections on the discovery GLP-1 as a satiety hormone: Implications for obesity therapy and future directions GLP-1 Agonists for Obesity: A
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There is also a concern about long term effects, so people with a history of pancreatitis, for example, would be unlikely to be prescribed a GLP-1

doi: 10.1681/ASN.2013070810

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There's the actual loss side of it okay, I've identified I've got some weight, I need to get rid of it