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They contribute to a mild reduction in androgen levels, evidenced by decreases in total testosterone and dehydroepiandrosterone sulfate (DHEAS), while simultaneously increasing sex hormone binding globulin (SHBG) levels

Even positive changes, such as weight loss, can stress the body and lead to temporary menstrual irregularities

Exendin-4/fibroblast growth factor 21 agonist, utilizing albumin-binding-designed ankyrin repeat proteins as carriers, displayed enhanced blood glucose lowering bioactivity and superior body weight management in the DIO mouse model

doi: 10.1016/j.jand.2024.10.023
