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Weight loss and balancing metrics like glucose and blood pressure play into consumers growing interest in longevity, which Dan covers as a key movement to watch for the coming year

Bellavance D, Chua S, Mashimo H (2025) Gastrointestinal motility effects of GLP-1 receptor agonists

Collectively, these data indicate that GLP-1 improves cardiac performance and output in the post-ischemic heart but otherwise may decrease cardiac output under non-pathological conditions

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hrbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Moher D

In this guide, well explain what GLP-1 RAs are, why they might cause nutritional deficiencies, and how you can prevent those deficiencies while on these medications