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Meanwhile, Wegovy 7.2 mg reduced abdominal fat a risk factor for chronic diseases, including type 2 diabetes, heart disease, high blood pressure, and stroke by 30%

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- In SURMOUNT-2, people taking Zepbound at the 15 mg dose experienced average weight reductions of 15.7% (34.4 pounds) and people taking Zepbound at the 10 mg dose experienced average weight reductions of 13.4% (29.8 pounds) compared to placebo 3.3% (7.0 pounds)

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Two of the most important ones are GLP-1 (Glucagon-Like-Peptide-1) and GIP (Glucose-dependent Insulinotropic Polypeptide)