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GLP-1 RAs showed several adverse gastrointestinal effects in non-diabetic patients with overweight or obesity

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That message is spreading like wildfire on TikTok about berberine, a compound found in plants such as barberry, golden seal and meadow rue that have a long history of use in Ayurvedic and Traditional Chinese Medicine

This is largely driven by rapid gastric emptying and an exaggerated GLP-1 mediated insulin response, particularly after Roux-en-Y gastric bypass (RYGB)

Compatible with many small TRT-style vials and similar containers