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Description

Thus, modulating the bioavailability and resorption of bile acids, the microbiota impacts on enterohepatic bile acid-signaling and greatly impacts the whole-body metabolic homeostasis (199)

The GIP receptor activation is not incidental

2 This effect may arise from mechanisms involving reduced ectopic fat accumulation and better cellular glucose uptake

Key active ingredients include Cissus CQR-300

In the Phase 2 retatrutide trial published in the New England Journal of Medicine (2023), participants at the highest dose (12 mg) achieved a mean body weight reduction of approximately 24.2% over 48 weeks