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There are some receptors, such as GPRC6A, with a pleiotropic distribution and still a limited understanding of its physiology

Metabolism 101:154001 Rezaei S, Tabrizi R, Nowrouzi-Sohrabi P, Jalali M, Atkin SL, Al-Rasadi K et al (2021) GLP-1 receptor agonist effects on lipid and liver profiles in patients with nonalcoholic fatty liver disease: systematic review and meta-analysis

A small number of people also had mild changes in heart rhythm (arrhythmias)