number of weight loss drug prescriptions q3 2024 semaglutide tirzepatide Chart: 1 in 8 Americans Now Use GLP-1 Drugs for weight loss drug prescriptions semaglutide

The future of obesity treatment is brighter than ever, and these medications are at the forefront

In practice, many experts believe the daily oral route may need a consistently high bioavailability to rival weekly shots

That finding is notable because tirzepatide achieved larger and faster weight reductions while also showing lower documented rates of several adverse events

Obesity patterns in the U.S

Phentermine (Adipex-P): What It Is: Sympathomimetic amine (stimulant) Appetite suppressant Oldest weight loss medication still available Effectiveness: Average Weight Loss: 5-7% of body weight Short-term use only (FDA-approved for 12 weeks) Weight often regained after stopping Mechanism: Stimulates norepinephrine release Decreases appetite Increases energy expenditure Side Effects: Increased heart rate and blood pressure Insomnia Nervousness, anxiety Dry mouth Constipation Potential for dependence Major Limitations: Controlled substance (Schedule IV) FDA-approved for short-term only (12 weeks) Not a long-term solution Cardiovascular concerns Risk of abuse Cost: Generic: $20-$50/month Usually not covered by insurance Who Should Consider: Need short-term appetite suppression Kickstart weight loss before switching to long-term option Cant afford other medications No cardiovascular disease or substance abuse Most experts dont recommend phentermine due to short-term limitation and rebound weight gain