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Description
They first began to think about this possibility in 1967 after detecting a rise in immunoreactive glucagon levels in the plasma of a patient after ingesting glucagon orally who had no pancreas
Combining GLP-1s with hormone therapy (HT) may improve outcomes, with studies showing up to 35% more weight loss than GLP-1s alone (6)
Weight loss is typically more modest than Wegovy but still clinically significant
Final recommendation statement
This results in an altered metabolic output, characterized by increased production of SCFAs and favorable modulation of bile acid profiles (5355)
