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Description
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Introduction GLP-1 receptor agonists (GLP-1RAs) have rapidly increased as a treatment for type 2 diabetes mellitus and obesity due to their effectiveness in improving glycemic control, promoting weight loss, and offering cardiovascular benefits [1]

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Both agents can also lead to vasodilation and thus whether hypotension worsens may depend on how effectively these agents assist in augmenting LV preload compared to systemic vasodilation
Orforglipron is oral, non-peptide, and doesnt require food timingmaking it a potential game-changer for patients who prefer pills over injections
