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Although causal incremental benefit cannot be established because of the single-arm design without a 0.5-mg maintenance comparator, these findings may support clinical decision-making regarding dose intensification in patients experiencing suboptimal control with 0.5-mg semaglutide

For elective surgery requiring general anesthesia, tirzepatide should be held for 4 weeks (approximately 3 half-lives) before the procedure to minimize aspir...

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