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Leptin-deficient ( ob/ob ) mice and humans with congenital deficiency of leptin have both metabolic disturbances and immune abnormalities, including abnormal cytokine secretion and thymic hypotrophy

Neither compound should be considered a licensed medicine in the UK, and both require careful scrutiny before any consideration of use

PMC2584810 Son MJ, et al

stimulant laxatives should be reserved for short-term use
