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To this end, our group has found that enhanced beta-cell GLP-1R signaling activates alpha-cell GLP-1 production ( Role of the alpha-cell in GSIS Proglucagon-derived products signal through the beta-cell GLP-1 receptor and glucagon receptor to potentiate GSIS Evaluation of the mechanisms by which beta-cell GLP-1R activation potentiates insulin secretion offers insight into the propensity for alpha-cell-derived proglucagon products to modulate beta-cell function
Previous research reports the presence of glucagon-like peptide-1 (GLP-1) receptors on neurons that produce glutamate
On GLP1 and feeling low energy, off digestion, or weird cravings
