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Jakafi (ruxolitinib) Indication(s): Intermediate or highrisk myelofibrosis, polycythemia vera (after hydroxyurea failure), acute graftversushost disease (GVHD) and chronic GVHD in adults (and pediatric patients 12 years and older) Manufacturer(s): Incyte (in the US)/Novartis 2024 Sales: $4.73 billion Why it sold so well: Jakafi generated approximately $2.8 billion in sales in 2024, marking a solid 8% YoY increase

These are aimed at giving patients more flexibility, reducing the cost burden and making adoption of these anti-obesity therapies easier

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Include 25-35 grams of fiber daily from vegetables, fruits, legumes, and whole grains

[DOI] [PMC free article] [PubMed] [Google Scholar] 131.Dai Z., Coker O.O., Nakatsu G., Wu W.K., Zhao L., Chen Z., Chan F.K., Kristiansen K., Sung J.J., Wong S.H., et al