gip/glp-1 agonist GLP-1 & GIP Agonists | Obesity and Diabetes Management | Harrison's updates (22nd Ed.) Potential Use of GLP-1 and
Description
In mice, liraglutide blunts hypertension induced by angiotensin II (Ang-II), an effect that is absent in GLP-1R KO mice, and is also attenuated upon pretreatment of WT mice with exendin (939) [640]

Nature 490 , 508513 (2012) Yang, L

GLP-1s dont look addictive in the same way

2 GLP-1 signaling within hypothalamic circuits of the brain activates satiety-promoting neurons and inhibits hunger-promoting neurons
Comparison of the effects of Liraglutide, Tirzepatide, and Retatrutide on diabetic kidney disease in db/db mice