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What our study suggests is something broader: GLP-1 drugs may also quiet what I call drug noise, the relentless craving that drives addiction across substances

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GLP-1 is rapidly degraded by dipeptidyl peptidase 4 (DPP-4), and the half-life of GLP-1 is approximately 2 minutes [3]

Interestingly, some brands of oral semaglutide, such as Rybelsus, have different formulations and might contain absorption enhancers like salcaprozate sodium