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But for many, especially people without qualifying conditions, it makes sense to be extremely cautious: Because Medicare right now will pay only in certain cases (not for weight loss alone)

Greger cuts through the promotional puffery and presents the pros and cons of these weight-loss drugs so individuals can make up their own mind in the face of the very real and devastating consequences of obesity

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Below, we summarize key studies evaluating GLP-1R agonism in rodent models of opioid reinforcement, seeking, withdrawal, and relapse

Concerns about thyroid cancer risk and the potential for sarcopenia or bone fragility in older patients further underscore the need for long-term surveillance (Nunn et al., 2024)
