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Description
Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists
Recently, peripheral leptin resistance especially leptin resistance in muscle, has drawn more attention, which may provide new insights into the treatment of obesity [220]
The difference before and after treatment was statistically significant
Based on this, we synthesized a panel of exendin-4 analogs with single amino acid substitutions close to the N-terminus, which we hypothesized could modulate receptor trafficking and/or signaling (Supplementary Fig
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