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In contrast, patients with T2DM who have not undergone bariatric procedures fully responded to the DPPIV inhibitor with improved glucose tolerance and insulin secretion, when it was combined with exendin(9-39) (75)
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The side effect and safety profile were like those observed with GLP-1 receptor agonists and GIP/GLP-1 receptor co-agonists with mild to moderate gastrointestinal events occurring mostly during dose escalations [64]
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