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Under these conditions of only mild hyperglycemia, the investigators did not observe major changes in bladder weight, or contractile responses to carbachol or KCl, or relaxant responses to several general or 2 - or 3 -adrenoceptor-selective agonists or forskolin

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Many patients find that eating smaller, more frequent meals, staying well hydrated, and avoiding very fatty or rich foods helps manage any nausea or digestive discomfort during the adjustment period