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54 A nationwide cohort study of 120,054 patients with type 2 diabetes over a median follow up of 7.4 years found an 11% reduction in the rate of dementia with GLP-1 receptor agonists (95% of patients were on liraglutide) when used as a second-line treatment compared with other glucose-lowering therapies, with greater benefit seen with longer duration of use

Special interests in diagnostic and procedural ultrasound, medical education, and ECG interpretation

Hormonal Considerations and Menstrual Cycles Significant weight loss affects hormonal balance, and Retatrutides metabolic effects may influence menstrual cycles directly

Risks include addiction and potential cardiovascular complications

Additionally, chronic treatment with GLP-1 RAs increases the abundance of anti-inflammatory microbial taxa (e.g., Bacteroidetes), which has been associated with improvements in both mood and glycemic control [94,95,99]