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After the first week off GLP-1, many people shift from transition mode into maintenance rhythm

It has been shown that exendin-4 enhanced the proliferation and differentiation of osteoblasts partly mediated by MAPK pathways, including ERK1/2, p38, and JNK pathways (48)

Five of the eight studies utilised liraglutide exclusively [41,42,43,44,47], two used liraglutide and exenatide (in separate patients) [45,46], and one used semaglutide [48]

These therapies offer a promising new approach to improving overall health in CKD patients

Recent study results shared at the Endocrine Society meeting ENDO 2026 indicate that semaglutide was linked to higher weight loss and a 15% decrease in broken bones when it was compared to other weight loss medications