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As for safety, the mid-stage trial found Ziihera to be well-tolerated, with only two patients discontinuing treatment due to toxicities

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found exendin-4 increased the expression of BDNF in mouse neocortex (178)
By one year, more than 40% of participants had lost at least 20% of their body weight
2.5 Pharmacokinetic, Safety, and Statistical Analyses Summary statistics and statistical analyses were based on all subjects exposed to a 0.5 mg dose of semaglutide
