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Semaglutide lowered heart attack and stroke risk versus sitagliptin, while tirzepatide performed comparably to dulaglutide and semaglutide over one year.

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The dual incretin agonist tirzepatide reduced 24-hour ambulatory BP for adults with obesity-related hypertension, with the effects potentially independent of weight loss, according to data from a planned substudy of the SURMOUNT-1 trial.“Tirzepatide led to clinically meaningful reductions in ambulatory blood pressure among adults with overweight and obesity, with reductions in the range

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Chow, MD, FACP, for Effective Treatment.
