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According to a study published in the New England Journal of Medicine examining semaglutide, participants receiving once-weekly semaglutide alongside lifestyle intervention experienced a mean weight loss of 14.9% from baseline over 68 weeks, compared with 2.4% for placebo plus lifestyle intervention

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Figure 1 gives an overview of the physiological actions of GLP-1 and GIP on various organ systems (47)

Effects of prebiotics on postprandial GLP-1, GLP-2 and glucose regulation in patients with type 2 diabetes: A randomised, double-blind, placebo-controlled crossover trial