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Description
THR also has a direct receptor-ligand interaction with the MAF bZIP transcription factor A (MAFA) promotor

As of January 31, 2026, 77.8% had engaged on or after week 4

Patients often retain reduced resting energy expenditure, persistent insulin resistance, and improved inflammatory markers that collectively create a metabolic headwind against weight loss

Regular monitoring as recommended by your prescribing clinician is essential

Moody AJ, Thim L, Valverde I