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The addition of GIP activation clearly enhanced metabolic outcomes compared to GLP-1 alone

1,2 To date, MAFLD has become a global health issue, accounting for 25% in Western countries 3 and 2530% in the Asia Pacific region

For individuals sourcing either compound from unregulated online vendors, additional risks include contamination with unknown substances, incorrect dosing due to inaccurate labelling, and the use of non-sterile injection equipment, which can lead to serious infections including abscess formation or sepsis

Patients should never combine these medications without explicit guidance from their prescribing clinician , who can monitor for potential complications and adjust treatment plans accordingly